Fight against COVID-19:Nigeria raises hope for breakthrough as NCDC validates viral RNA extraction

            

The fight against COVID-19 is ongoing.

Nigeria has recorded a breakthrough in Africa with the Nigeria Centre for Disease Control (NCDC) successfully validating the first phase of the viral Ribonucleic Acid (RNA) extraction which could enable local production of cheap testing kits for corona virus.

The validation happened on Thursday in the laboratory of the National Biotechnology Development Agency (NABDA) in Abuja.

The Director-General of NABDA, Prof. Alex Akpa, told the News Agency of Nigeria (NAN) after the move that the success of the validation was significant not only to Nigeria but Africa as a whole.

“The success of this validation will enable us to massively produce test kits to make it easier for people to be tested for COVID-19, not only in Nigeria but in Africa.

The immediate aim is to produce reagents for real time Polymerase Chain Reaction (PCR), and remember, recently the lack of reagents stalled work in Kano and molecular diagnosis could no longer take place,’’ Akpa stated.

He also explained that the absence of the same reagent equally stalled COVID-19 diagnosis in Lagos for many days.

This project is, therefore, designed to help not only Nigeria but the whole of Africa to put the issue of shortage of reagents behind,’’ the director-general added.

He revealed that the project was a Pan-African project whose partners include Ethiopia, NCDC and the University of Sheffield, U.K., among others with funding to come from African Development Bank.

Dr Ndodo Nnaemeka, Chief Molecular Bioengineer, National Reference Laboratory of NCDC, indicated that he was mandated by the NCDC Director-General, Dr Chikwe Ihekweazu, to “launch this wonderful project.’’

According to Nnaemeka, the project is designed to address the problem of RNA extraction kit which had become a global issue.

He explained that there were serious concerns for the need to have more extraction kits in the country, and that there was growing demand worldwide for extraction kits.

"The western world prioritises their own interest first by making sure that they meet their local needs before exporting to other countries, so there was really need for it,’’ he said,

The NCDC chief molecular bioengineer disclosed that the first phase of the evaluation results he carried out with the NABDA scientific team was “awesome and successful.’’

" The kits compete favourably well with other international kits we are using, in fact, it scored highly in purity and in quantity of extraction and we are thinking of scaling production,’’ Nnaemeka stated.

He explained that to be able to conduct test, the viral information which comes as the RNA has to be extracted first and without this extraction, no test can be carried out.

"What will tell you that the virus is there is contained in the RNA, so RNA is required for you to be able to detect COVID-19,’’ he stated.

               

                   

He announced that as scientists, they would soon carry out the second phase of the evaluation which would include real sample of COVID-19.

Similarly, Dr Rose Gidado, a scientist at NABDA and Country Coordinator, Open Forum on Agricultural Biotechnology (OFAB), stated that the exercise was historic.

She disclosed that the validated RNAswift Test Kit for COVID-19 was developed by Dr Alison Nwokeoji, a Nigerian scientist at the University of Sheffield, U.K.

She revealed that the African Development Bank was taking over the manufacture of the test kits in order to expand Nigeria’s testing capacity with emphasis on farmers’ health.

Gidado also disclosed that the new test kit has the capability to test more than 20,000 people per day.

" If we set up more testing centres, we can easily do 50,000 with automation,’’ the scientist stated.

She said  the project was a partnership including NABDA, NCDC, Ethiopia, NVRI Vom, NIMR and the Ministries of Science and Technology, Health and Agriculture.

NAN reports that the evaluation and validation of the RNAswift Test Kit for COVID-19 took pkace in the immunology laboratory of the NABDA.

The event took place in the presence of a donor, Mr Bolaji Akinboro of Cellulant Nig. Ltd, and Mr Richard Mbaram, the Technical Adviser to the Minister of Agriculture and Rural Development, Alhaji Sabo Nanono, to name a few.